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 CURRENT TOP 10 BY F1000 FACTOR | ALL OF MEDICINE | calculated on 9 May 2008

"Current Top 10 By F1000 Factors" are generated every day using only papers added to F1000 Medicine over the last 30 days. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.

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1
Exceptional
F1000 Factor 10.5
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

Confirmation
New Finding
 Treatment of hypertension in patients 80 years of age or older.
Beckett NS, Peters R, …, Bulpitt CJ, HYVET Study Group
N Engl J Med 2008 May 1 358(18):1887-98 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Deepak Bhatt with Dharam Kumbhani / Ramachandran S. Vasan / Jerome Fleg / Annemarie Hennessy / Ernesto Schiffrin / Wilbert Aronow
First evaluation 14 Apr 2008 | Latest evaluation 7 May 2008
 
2
Exceptional
F1000 Factor 9.0

Hypothesis
 Contaminated Heparin Associated with Adverse Clinical Events and Activation of the Contact System.
Kishimoto TK, Viswanathan K, …, Woodcock J, Sasisekharan R
N Engl J Med 2008 Apr 24 [abstract on PubMed] [related articles] [FREE full text]
Selected by | Jerrold Levy
Evaluated 9 May 2008
 
3
Exceptional
F1000 Factor 9.0

Hypothesis
New Finding
 Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation.
Niessen F, Schaffner F, …, Rosen H, Ruf W
Nature 2008 Apr 3 452(7187):654-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Philipp M Lepper
Evaluated 7 May 2008

 
4
Exceptional
F1000 Factor 9.0
Articles that inform your practice or change your way of thinking Changes
Clinical Practice

New Finding
 The influence of baseline hemoglobin concentration on tolerance of anemia in cardiac surgery.
Karkouti K, Wijeysundera DN, …, van Rensburg A, Beattie WS
Transfusion 2008 Apr 48(4):666-72 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | John Augoustides
Evaluated 7 May 2008
 
5
Exceptional
F1000 Factor 9.0

Hypothesis
 Role of left ventricular stiffness in heart failure with normal ejection fraction.
Westermann D, Kasner M, …, Schultheiss HP, Tschöpe C
Circulation 2008 Apr 22 117(16):2051-60 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Jan Poelaert
Evaluated 1 May 2008
 
6
Exceptional
F1000 Factor 9.0

Hypothesis
New Finding
 Antiribosomal-P autoantibodies from psychiatric lupus target a novel neuronal surface protein causing calcium influx and apoptosis.
Matus S, Burgos PV, …, Jacobelli S, González A
J Exp Med 2007 Dec 24 204(13):3221-34 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Christopher Ritchlin with Roger Wang
Evaluated 30 Apr 2008

 
7
Exceptional
F1000 Factor 9.0

Confirmation
 Osteoarthritis.
Goldring MB, Goldring SR
J Cell Physiol 2007 Dec 213(3):626-34 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Thomas Aigner
Evaluated 29 Apr 2008
 
8
Exceptional
F1000 Factor 9.0

Tech Advance
 Visualizing spatiotemporal dynamics of multicellular cell-cycle progression.
Sakaue-Sawano A, Kurokawa H, …, Masai H, Miyawaki A
Cell 2008 Feb 8 132(3):487-98 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Chou-Zen Giam
Evaluated 28 Apr 2008

 
9
Exceptional
F1000 Factor 9.0

Confirmation
 Inflammation and metabolic disorders.
Hotamisligil GS
Nature 2006 Dec 14 444(7121):860-7 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Marc Jeschke
Evaluated 25 Apr 2008
 
10
Exceptional
F1000 Factor 9.0

New Finding
 Endocrine disruptors and the thyroid gland--a combined in vitro and in vivo analysis of potential new biomarkers.
Schmutzler C, Gotthardt I, …, Wuttke W, Köhrle J
Environ Health Perspect 2007 Dec 115 Suppl 1:77-83 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Ulla Feldt-Rasmussen
Evaluated 25 Apr 2008

 
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